As a neonatologist I hate H2 blockers (and PPIs)- very few cases where it improves things and many unfavorable effects that worsen immunity and alter microbiome. But interesting (though scientifically way too early to tell) to see if it benefits PMDD! We definitely need more treatments for PMDD, postpartum depression and other conditions that so many people deal with.
Food allergies down the line, aberrant microbiome and pneumonias. It’s on the Choosing Wisely do not use list, for good reason. But so cool to consider a new use for an established and most importantly easily available medication! Great post.
While we're talking about pepcid in the context of MCAS... Can using pepcid long term as one of the treatments for MCAS cause similar gut issues mentioned in the article and comments such as constipation, microbiome changes, and absorption issues (both nutrients and other medications)?
I don’t have PMDD or PMS but take Famotidine and have noticed my allergy symptoms are better, my sinuses are clearer. Very interesting. You didn’t mention Xyzal, what blocker is it?
Interesting that PMDD is listed in the DMS-5 identifying it as a psychological disorder. Is this because of the interplay of serotonin and GABA, or is this another example of identifying women's symptoms as "hysteria"?
As someome who has PMDD, the only thing that ever helped me is not ovulating.
As a female who suffers from PMDD this is very interesting! 🤔 I’ll keep my eye on this!
I hope the post helped!
As a neonatologist I hate H2 blockers (and PPIs)- very few cases where it improves things and many unfavorable effects that worsen immunity and alter microbiome. But interesting (though scientifically way too early to tell) to see if it benefits PMDD! We definitely need more treatments for PMDD, postpartum depression and other conditions that so many people deal with.
I agree that lowering stomach acid production is potentially problematic in infants. May be associated with developing food allergies.
Food allergies down the line, aberrant microbiome and pneumonias. It’s on the Choosing Wisely do not use list, for good reason. But so cool to consider a new use for an established and most importantly easily available medication! Great post.
Thank you so much! 😊
There’s got to be a source that doctors can find. Or some way to. Or just treat the symptoms. I hope!
Can you make a post about MCAS? I would like to know more about what options I have to control it.
I will in the future. Also I have a chapter about mast cell disorders in my book coming out next year!
While we're talking about pepcid in the context of MCAS... Can using pepcid long term as one of the treatments for MCAS cause similar gut issues mentioned in the article and comments such as constipation, microbiome changes, and absorption issues (both nutrients and other medications)?
I don’t have PMDD or PMS but take Famotidine and have noticed my allergy symptoms are better, my sinuses are clearer. Very interesting. You didn’t mention Xyzal, what blocker is it?
Xyzal is levocetirizine which is a H1 antihistamine like Zyrtec
Thanks!
Interesting that PMDD is listed in the DMS-5 identifying it as a psychological disorder. Is this because of the interplay of serotonin and GABA, or is this another example of identifying women's symptoms as "hysteria"?
I have a sibling who suffers from PMDD so this can be very helpful thank you
Yeah I tried it. Did nothing
I have PMDD. I also break out in hives before my period. I'm hopeful progress is made on this research.
Allergic to being female is fun
I thank you for encouraging research into this and a disorder that robs some women of a percentage of their lives feeling good!